You should avoid taking any MAO inhibitors while using trazodone. Monoamine oxidase (MAO) inhibitors can interact with trazodone in a potentially fatal manner, according to WebMD.This is why it is important to never use drugs like trazodone on a whim. Your doctor understands these risks and knows how to avoid drug interactions. The drug interacts with a high number of other medications. If you are a multiple health condition sufferer, you open yourself up to more risks by using trazodone for insomnia. At any rate, it is safe to conclude that you should not drive a vehicle while under the effect of trazodone. What is worse still is that the above lists do not cover all possible trazodone side effects.Īs to the discomfort and danger, these side effects entail, some are obvious, others less so. The bottom line is that trazodone use may promote the very problems you are trying to solve with it. This is contradictory, as the drug is used to combat these two conditions among others. If the above side effects are not enough to dissuade you from using trazodone as a sleep aid, consider the following: trazodone’s side effects include insomnia and anxiety. Considering self-harm (mostly in teenagers and children).Some side effects are more severe than the above. Those who use it to this end face several mild and serious side effects. Trazodone Side-effectsĪs mentioned, despite its popularity, trazodone is far from an ideal solution for insomnia. That said, the mentioned study concludes that science does not currently understand everything about its mechanism of action. The main pharmacological action of trazodone is serotonin receptor blocking. From the perspective of insomnia, it is also significant that trazodone impacts the cortisol suppression of the hypothlamic-pituitary-adrenal axis. On the other hand, it also inhibits serotonin reuptake. On the one hand, it is a serotonin antagonist, meaning that it mimics the effects of the neurotransmitter. It acts upon the neurotransmitter serotonin. If you are at all interested in dreaming and sleep in general, you will probably find it very interesting.Ī 2017 systematic review, by Tiffany Chang, Brigitte Vanle, Karim Yahia Jaffer, et al., on the use of trazodone for insomnia, took a close look at the pharmacology of the drug.Īpproved in 1982 for the treatment of depression, trazodone is a triazolopyridine derivative. The pharmacology of this drug explains why so many doctors prescribe it for insomnia. They do so being fully aware of the pharmacology of the prescribed drug. Doctors routinely make such prescriptions. What you should know about off-label medicine use is that it is not uncommon at all. That said, its off-label use for this purpose is widespread. It is currently not approved for the treatment of insomnia. Trazodone is an FDA-approved drug for the treatment of depression. 7 Levels of Consciousness, Chakras, & Sephirotħ The Bottom Line on Trazodone for Sleep What is Trazodone? How Does it Work?.Excessive Dreaming (Why Am I Dreaming More?).Lucid Dreaming for Athletes (Welcome to Dream Gym).21 Best Herbs & Supplements for Lucid Dreaming.
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